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Treating / Managing IBD

• What IS Feline Inflammatory Bowel Disease (IBD)?
• Feline Nutrition in Inflammatory Bowel Disease
• The Raw Feeding for IBD Cat Group's Alternative Protocol for Treatment
• Raw Feeding and IBD in Cats
• Bone Broth for IBD
• How to Use Baby Food or A Plain Diet
• Prebiotics & Probiotics for Cats - A Cornerstone of Health & Healing in Feline IBD
• ***Consider a Fecal Microbiota Transplant pill - the only species specific, colonizing option to restore a healthy microbiome in your cat.  AnimalBiome's Gut Restoration pills are created from the stool of carefully screened cats with a healthy microbiota. Please see Healing Your Pet with a Fecal Microbiota Transplant
  
• Why You SHOULD Feed Your Immune Compromised Cat Raw Food
• Is it IBD or Cancer? Diagnosing & Treating Feline IBD vs Lymphoma

Related Problems

• Constipation - Help! My cat is constipated - what do I do? How to use fat and fibers to manage constipation.
• Diarrhea - How to Use S boulardii
  
• Diarrhea - Help! My cat has diarrhea - what do I do? Broader instructions for a bout of acute diarrhea in healthy cats are the same for management of chronic diarrhea in cats with IBD (though as discussed in managing diarrhea in the Probiotics for Cats, testing for B12 levels, exocrine pancreatic insufficiency (EPI), hyper-thyroid, etc. should be done as they are concurrent health issues that can cause diarrhea). Specific instructions for use of S boulardii are here.
  
• Food Sensitivities - Alternative Protocol for Treatment file.
  
• Hairballs - How Best to Treat Them
• Hairballs - How to Make Homemade Dried Egg Yolk Powder
  
• Nausea in Cats - Including Slippery Elm Bark Powder Instructions
• Nausea in Cats - What is fed, How it is Fed, and When it is Fed
• Pilling, Assist Feeding & Finger Swiping
• Vomiting: Help! My cat is vomiting - what do I do? Includes discussion of managing vomiting due to acid build-up, otherwise known as "acid pukes," "bile pukes," and "hunger pukes."
• Vomiting: see The Pepcid Series.

Supporting Information / Helpful Links

• Chronic Vomiting in Cats is NOT Normal - Norsworthy 2014
• Feline IBD/Diarrhea: The Good (Diets), The Bad (Bacteria), and the Ugly (Diagnosis) - Zoran 2010

For those who want to get more in-depth, here are the sources for information presented in many of our discussions and files.


The Research in Humans

• Ghosh et al. 2004. Probiotics in inflammatory bowel disease: is it all gut flora modulation? Gut. 2004 May; 53(5): 620–622. 
• Peña et al. 2005. Probiotic Lactobacillus spp. Diminish Helicobacter hepaticus-Induced Inflammatory Bowel Disease in Interleukin-10-Deficient Mice, Infect Immun. 2005 Feb; 73(2): 912–920. 
• The Article: Chow & Mazmanian 2010. Caltech Biologists Link Gut Microbial Equilibrium to Inflammatory Bowel Disease
• The Study:  Chow J and Mazmanian SK 2010. A pathobiont of the microbiota balances host colonization and intestinal inflammation. Cell Host Microbe. 2010 Apr 22;7(4):265-76. 
• The Article: Elinav et al, Yale News 2011. Immune System Malfunction May Trigger Inflammatory Bowel Disease.
• The Study: Elinav et al. 2011. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.  Cell. 2011 May 27;145(5):745-57. 
• Comito , D and Romano C. 2012. Dysbiosis in the Pathogenesis of Pediatric Inflammatory Bowel Diseases, Intl. Jour of Inflammation Vol 2012, Article ID 687143, 7 pages.
• Denizot et al 2012. Importance of Bacteria as Trigger in Inflammatory Bowel Disease. J Gastroint Dig Syst 2012, S8. 
• The Article: Khounlotham et al, Emory News 2013.  Immune system compensates for 'leaky gut' in IBD susceptibility.
• The Study: Khounlotham et al. 2013. Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis. Immunity. 2012 Sep 21; 37(3): 563–573. 
• The Article: Winter et al, UC Davis Health System News 2013. Scientists find key to growth of "bad" bacteria in inflammatory bowel disease. 
• The Study: Winter et al 2013. Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut. Science 8 February 2013: Vol. 339  no. 6120  pp. 708-711. 
• The Article: Silva et al 2013, University of Arizona News. Putting the Brakes on Inflammation.
• The Study: Silva et al. 2013. T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response, Immunity Vol 39, Issue 1, p160–170, 25 July 2013. 

The Research in Cats

• LE Ritchie 2008. Molecular characterization of intestinal bacteria in healthy cats and a comparison of the fecal bacterial flora between healthy cats and cats with inflammatory bowel disease (IBD), MS Thesis, Texas A&M, Veterinary Medical Sciences.
• Janeczko et al. 2008. The relationship of mucosal bacteria to duodenal histopathology, cytokine mRNA, and clinical disease activity in cats with inflammatory bowel disease, Vet Microbiol 128 (2008) 178-193.
• Desai et al 2009. Characterization and quantification of feline fecal microbiota using cpn60 sequence-based methods and investigation of animal-to-animal variation in microbial population structure, Vet Microbiol 2009 May 28;137(1-2):120-8.
• JF Garcia-Mazcorro and Y Minamoto 2013. Gastrointestinal microorganisms in cats and dogs: a brief review, Arch Med Vet 45, 111-124 (2013).
• Honnafer, Minamoto, Suchodolski 2014. Microbiota alterations in acute and chronic gastrointestinal inflammation of cats and dogs, World J Gastroenterol. 2014 Nov 28; 20(44): 16489–16497. 
  
• Suchodolski et al. 2015.  The Fecal Microbiome in Cats with Diarrhea, PLoS ONE 10(5): e0127378. doi:10.1371/journal.pone.0127378.